A portion of Manchester United fans were involved in the protest against the Glazers outside Old Trafford on the opening day defeat to Brighton.
#EmptyOldTrafford is now trending on Twitter with shouts to boycott United's next home fixture against Liverpool.
Last season, the match against Liverpool was postponed due to the anti-Glazer protest and some fans even stormed the pitch.
Fans will now be hoping to make a statement with another major protest and over 55,000 posts on Twitter were dedicated to the protest.
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